Education
- 2023: Postdoc at Western University, Canada
- 2023: PhD from the University of Manitoba, Canada
- 2019: MSc from the University of Manitoba, Canada

Dr. Qian Liu is an Assistant Professor in the Department of Applied Computer Science at the University of Winnipeg. She is trained in machine learning, deep learning, applied statistics, bioinformatics, computational biology, and medical imaging. Dr. Liu holds a Ph.D. in Individual Interdisciplinary Studies, which integrates Computer Science, Statistics, and Medical Genetics.

Dr. Liu's research lab is dedicated to developing and applying advanced data science techniques, such as multi-modal data integration (including genomics, imaging, time-series, and graph data), joint statistics and machine learning, and interpretable artificial intelligence (AI). Her work addresses specific challenges in healthcare and material science, aiming to improve diagnostic accuracy, treatment planning, and the development of new materials.

Dr. Liu’s expertise in AI, statistics, and bioinformatics synergizes with the diverse skills of her collaborators. Her multidisciplinary and collaborative framework enhances the impact of her research, making significant contributions to both healthcare and material science.


Qian Liu

Ph.D.

Department of Applied Computer Science
University of Winnipeg
Winnipeg, MB, Canada
Email: qi.liu~at~uwinnipeg.ca

Teaching

  • ACS-3953 Intro to AI (2023-2025)
  • GACS-7205 Digital image processing (2023-2025)
  • ACS-3947 Algorithm design (2023-2025)
  • 2025 Fall ACS-4930 HRI for surgical training
  • 2024 Fall GACS-7401 AI in materials informatics
  • 2024 SS GACS-7401 AI in neuro radiogenomics
  • 2024 Winter ACS-4930 AI in proteomics
  • Publications

    co-first author *
    co-corresponding author **
    trainee

    2025

    42. S Dharia, Q Liu, S Smith, C Valderrama
    Dual-Transformer Cross-Attention Framework for Alzheimer’s disease detection via dPTE-Guided EEG channel selection and multi-modal integration
    Biomedical Signal Processing and Control. https://doi.org/10.1016/j.bspc.2025.108390.
    41. M Kaur, S Ramanna, Y Chen, Q Liu
    PolyGraphCL: A Multi-View Graph Contrastive Learning Framework for Grain-Level Fatigue Damage Prediction in Polycrystalline Materials
    IEEE Sensors Journal. https://doi.org/10.1109/JSEN.2025.3598238.
    40. M Tahir, S Ramanna, Q Liu
    Hybrid Representation Learning for Human m6A Modifications with Chromosome-Level Generalizability
    Bioinformatics Advances 5(1). https://doi.org/10.1093/bioadv/vbaf170.
    39. X Zhang, S Wijenayake, Q Liu
    Estimating Progression of Alzheimer's Disease with Extracellular Vesicle-Related Multi-Omics Risk Models
    Frontiers in Aging Neuroscience 17: 1617611. https://doi.org/10.3389/fnagi.2025.1617611.
    38. Y Abdelkader, M Abdelkarim, M Suresh, T Lopera, S Dhaliwal, S Shojaei, L Pope, Q Liu, P Hu, H Haga, K Thu, S Giunta, S Ishihara, M Anikovskiy, H Labouta
    Genomic instability and shear stress influence nanoparticle-induced endothelial cell responses and gene expression
    Materials Today Nano 31: 100641. https://doi.org/10.1016/j.mtnano.2025.100641.
    37. A Ebadi, M Kaur, Q Liu
    Hyperparameter optimization and neural architecture search algorithms for graph neural networks in cheminformatics
    Computational Materials Science 254: 113904. https://doi.org/10.1016/j.commatsci.2025.113904.
    36. Q Liu, D Fung, H Liu, P Hu
    Knockoff statistics-driven interpretable deep learning models for uncovering potential biomarkers for COVID-19 severity prediction
    International Conference on Learning Representations (ICLR) 2025 workshop
    35. M Kaur, C Valderrama, Q Liu
    Hybrid vision transformer framework for efficient and explainable SEM image-based nanomaterial classification
    Machine Learning: Science and Technology 6: 015066.https://doi.org/10.1088/2632-2153/adc072.
    34. H Liu, X Zhang, Q Liu
    A review of AI-based radiogenomics in neurodegenerative disease
    Frontiers in Big Data 8: 1515341.https://doi.org/10.3389/fdata.2025.1515341.
    33. X Zhang, Q Liu
    A graph neural network approach for hierarchical mapping of breast cancer protein communities
    BMC Bioinformatics 26(23).https://doi.org/10.1186/s12859-024-06015-x.

    2024

    32. L Chen, ZH Huang, Y Sun, M Domaratzki, Q Liu**, P Hu**
    Conditional Probabilistic Diffusion Model Driven Synthetic Radiogenomic Applications in Breast Cancer
    Plos Computational Biology. 20(10): e1012490. https://doi.org/10.1371/journal.pcbi.1012490.
    31. H Liu, CE Valderrama, X Zhang, Q Liu
    MPSleepNet: Matrix Profile-Guided Transformer for Multi-Channel Sleep Classification
    2024 International Conference on Signal Processing and Machine Learning (SPML). https://doi.org/10.1145/3686490.3686519.
    30. CE Valderrama, A Sheoran, Q Liu
    Exploring the Effect of Age and Sex on Subject-Independent EEG-Based Emotion Recognition Methods
    2024 IEEE Canadian Conference on Electrical and Computer Engineering (CCECE), pp. 319-323. https://doi.org/10.1109/CCECE59415.2024.10667058.
    29. Y Li, L Lac, Q Liu, P Hu
    ST-CellSeg: Cell segmentation for imaging-based spatial transcriptomics using multi-scale manifold learning
    Plos Computational Biology.https://doi.org/10.1371/journal.pcbi.1012254.
    28. YW Jin, P Hu, Q Liu
    NNICE: a deep quantile neural network algorithm for expression deconvolution
    Scientific Reports. 14, 14040. https://doi.org/10.1038/s41598-024-65053-w.
    27. R Qiu, X Zhang, C Song, H Nong, Y Li, X Xing, K Mequanint, Q Liu, X Sun, M Xing, L Wang
    E-cardiac patch to sense and repair infarcted myocardium
    Nature Communications. 15, 4133. https://doi.org/10.1038/s41467-024-48468-x.
    26. J Chowdhury, Q Liu, S Ramanna
    Simple histogram equalization technique improves performance of VGG models on facial emotion recognition datasets
    Algorithms. 17, 6: 238. https://doi.org/10.3390/a17060238.
    25. Z Huang, L Chen, Y Sun, Q Liu**, P Hu**
    Conditional generative adversarial network driven radiomic prediction of mutation status based on magnetic resonance imaging of breast cancer
    Journal of Translational Medicine. 22:226. https://doi.org/10.1186/s12967-024-05018-9.

    2023

    24. Q Liu, S Huang, D Desautels, KJ McManus, L Murphy, P Hu
    Development and validation of a prognostic 15-gene signature for stratifying HER2+/ER+ breast cancer
    Computational and Structural Biotechnology Journal. 21:2940-2949.
    23. D Fung, Q Liu, L Lac, L O'Neil, C Hitchon**, P Hu**
    Deep learning-based joint detection in Rheumatoid arthritis hand radiographs
    AMIA (American Medical Informatics Association) Jt Summits Transl Sci Proc . 206-215. PMID: 37350925. Seattle, Washington, USA.
    22. I Paul, D Bolzan, A Youssef, KA Gagnon, H Hook, G Karemore, MUJ Oliphant, W Lin, Q Liu, S Phanse, C White, D Padhorny, S Kotelnikov, CS Chen, P Hu, GV Denis, D Kozakov, B Raught, T Siggers, S Wuchty, SK Muthuswamy, A Emili
    Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT.
    Nature Communications, 14:688.
    21. Q Liu, S Huang, Z Zhang, T Lakowski, W Xu, P Hu
    Multiomics-based tensor decomposition for characterizing breast cancer heterogeneity
    Invited chapter for “Machine Learning Methods for Multi-Omics Data Integration” edited by Luis Rueda. Nature Springer -Verlag Press. 133-150.
    20. Q Liu, P Hu
    Radiogenomic association of deep MR imaging features with genomic profiles and clinical characteristics in breast cancer
    Biomarker Research, 11:9

    2022

    19. Q Liu*, M Reed*, H Zhu*, Y Cheng, J Almeida, G Fruhbeck, R Ribeiro, P Hu
    Epigenome-wide DNA methylation and transcriptome profiling of localized and locally advanced prostate cancer: uncovering new molecular markers
    Genomics, 114(5):110474.
    18. Y Su, Q Liu, W Xie, P Hu
    YOLO-LOGO: A transformer-based YOLO segmentation model for breast mass detection and segmentation in digital mammograms
    Computer Methods and Programs in Biomedicine,221:106903
    16. Q Liu, P Hu
    An integrative computational framework for breast cancer radiogenomic biomarker discovery
    Computational and Structural Biotechnology Journal, 20:2484-2494
    15. J Zammit, DLX Fung, Q Liu, CKS Leung, P Hu
    Semi-Supervised COVID-19 CT Image Segmentation Using Deep Generative Models
    BMC Bioinformatics, 23:343
    14. N Feizi, Q Liu, L Murphy, P Hu
    Computational prediction of the pathogenic status of cancer-specific somatic variants
    Frontiers in Genetics. 12:805656
    13. B Blum, W Lin, ML Lawton, Q Liu, J Kwan, I Turcinovic, R Hekman, P Hu, A Emili
    Multi-omic metabolic enrichment network analysis reveals metabolite-protein physical interaction subnetworks altered in cancer
    Molecular & Cellular Proteomics. 21 (1):100189
    12. Q Liu, P Hu
    Interpretable and extendable deep learning for pan-cancer radiogenomics research
    Current Opinion for Chemical Biology. 66:102111
    11. Q Liu*,B Cheng*, Y Jin, P Hu
    Bayesian tensor factorization-driven breast cancer subtyping by integrating multi-omics data
    Journal of Biomedical Informatics. 125:103958

    2021

    10. LJ Oneil, P Hu, Q Liu, M Islam, V Spicer, J Rech, A Hueber, V Anaparti, I Smolik, H EI-Gabalaway, G Schett, JA Wilkins
    Proteomic Approaches to Defining Remission and the Risk of Relapse in Rheumatoid Arthritis
    Frontiers in Immunology, 12:729681
    9. Q Liu*, D LX Fung*, L Lac*, P Hu
    A novel matrix profile-guided attention LSTM model for forecasting COVID-19 cases in USA
    Frontiers in Public Health, 9:741030
    8. D LX Fung*, Q Liu*, J Zammit, CK Leung, P Hu
    Self-supervised deep learning model for COVID-19 lung CT image segmentation highlighting putative causal relationship among age, underlying disease and COVID-19
    Journal of Translational Medicine. 19:318
    7. A Bruinooge*, Q Liu*, Y Tian, W Jiang, Y Li, W Xu, CN Bernstein, P Hu
    Genetic predictors of gene expression associated with psychiatric comorbidity in patients with IBD: a pilot study
    Genomics. 113: 919-932.
    6. R Ajwad, M Domaratzki, Q Liu, N Feizi, P Hu
    Identification of significantly mutated subnetworks in the breast cancer genome
    Scientific Reports. 11:642

    2020

    5. Q Liu, CK Leung, P Hu
    A two-dimensional sparse matrix profile DenseNet for COVID-19 diagnosis using chest CT image
    IEEE Access. 8:213718-213728

    2019

    4. Q Liu, A Junker, K Murakami, P Hu
    A novel convolutional regression network for cell counting
    2019 IEEE 7th International Conference on Bioinformatics and Computational Biology. Hangzhou, China
    Won Best Oral Presentation Paper
    3. Q Liu, A Junker, K Murakami, P Hu
    Automated cancer cell counting by ensembling deep features
    Cells, 8(9):1019
    2. Q Liu, P Hu
    Association analysis of deep genomic features extracted by denoising autoencoders in breast cancer
    Cancers. 11:494

    2018

    1. P Basak, S Chatterjee, V Bhat, A Su, H Jin, V Lee-Wing, Q Liu, P Hu, LC Murphy, A Raouf
    H19 acts as an estrogen receptor modulator that is required for endocrine therapy resistance in ER+ breast cancer cells
    Journal of Cellular Physiology and Biochemistry. 51:1518-1532

    News

    2025.9.3 Welcome Yuxi (MSc student) and Shenyu (MSc student) to join the lab!

    2025.8.29 Our MSc student Manpreet Kaur won Research Manitoba Master's Studentship Award. Congratulations!

    2025.8.29 Our MSc student Ali Ebadi won The University of Winnipeg Graduate Studdies Scholarship (UWGSS). Congratulations!

    2025.3.20 Welcome Max (NSERC USRA student) and Shuhan (Mitacs Global Link student) to join the lab!

    2025.1.1 Welcome Dr. Tahir (Postdoctoral Fellow) and Shyamal (Senior Research Assistant) to join the lab!

    2024.10.3 Dr. Qian Liu is selected and funded to attend the 2024 CIHR-ICR Early Career Researcher Workshop in Toronto. Congratulations!

    2024.9.11 Our MSc student Manpreet Kaur won The University of Winnipeg President’s Scholarship for World Leaders. Congratulations!

    2024.7.13 Our MSc student Huanjing Liu won the 2024 International Signal Processing and Machine Learning (SPML) Conference Best Oral Presention Award. Congratulations!

    2024.5.31 Dr. Qian Liu won the University of Manitoba Distinguished Dissertation Award. Congratulations!

    2024.3.5 Our undergraduate student Xiao Zhang won the NSERC USRA award. Congratulations!

    2023.8.4 Dr. Qian Liu's lab has now been established and is accepting graduate students, welcoming visiting scholars, and providing research opportunities for undergraduate students. If you are interested in engaging in research with Dr. Liu, please reach out via email to explore potential opportunities.

    Members

    Postdoctoral Fellow
    Dr. Muhammad Tahir (The University of Winnipeg)

    Senior Research Assistant
    Shyamal Dharia (The University of Winnipeg)

    Doctor of Medicine (MD) Student
    Xiao Zhang (Doctor of Medicine Program, University of Manitoba)
    Also accepted by the BSc (Med) Program, University of Manitoba

    MSc Student
    Huanjing Liu (Applied Computer Science, The University of Winnipeg)
    Recipient of the 2024 International Signal Processing and Machine Learning (SPML) Conference Best Oral Presention Award

    Manpreet Kaur (Applied Computer Science, The University of Winnipeg)
    Recipient of The University of Winnipeg President’s Scholarship for World Leaders
    Recipient of Research Manitoba Master's Studentship Award

    Ali Ebadi (Applied Computer Science, The University of Winnipeg)
    Recipient of The University of Winnipeg Graduate Studdies Scholarship

    Yuxi Wang (Applied Computer Science, The University of Winnipeg)

    Shenyu Yu (Applied Computer Science, The University of Winnipeg)

    Undergraduate Student
    Maximilien Oosterhuis (Applied Computer Science, The University of Winnipeg)
    Recipient of the NSERC USRA Award

    Shuhan Wang
    Recipient of the Mitacs Global Link Research Internship Award

    Dristi Rauniyar (Applied Computer Science, The University of Winnipeg)

    Past Members

    Undergraduate Student
    Xiao Zhang (Applied Computer Science, University of Winnipeg)
    Recipient of the NSERC USRA Award
    Period: Janurary 2024 - September 2024.
    Current Position: MD student, University of Manitoba

    Positions

    Dr. Liu is currently open to accepting graduate students, welcoming visiting scholars, and providing research opportunities for undergraduate students. If you are interested in engaging in research with Dr. Liu, please reach out via email to explore potential opportunities.

    Selected Grants

  • NSERC Discovery Grant – principal applicant
  • MMSF Research Operating Grant – principal applicant
  • CFI-JELF – principal applicant
  • CIHR Spring Project Grants – co-applicant
  • Arthritis Society Canada Ignite Innovation Grants – co-applicant